Which neurotoxin works the fastest Botox or Dysport?

Dysport, Jeuveau, and Daxxify show visible results in 2–3 days with full effect by day 7, while Botox and Xeomin take 3–7 days for visible results and 14 days for full effect. If your patients prioritize speed, stocking Dysport or Daxxify gives you a competitive advantage in marketing faster results.

How long does Daxxify last compared to other neurotoxins?

Daxxify lasts up to 6 months, roughly double the 3–4 month duration of Botox, Dysport, Jeuveau, and Xeomin. This extended duration reduces patient visit frequency, which can lower annual revenue per patient but appeals to busy clients seeking longer intervals between treatments.

Why does Dysport require more units than Botox?

Dysport is 2.5–3× less potent per unit than Botox, so a typical glabellar dose requires ~50 Dysport units versus ~20 Botox units for equivalent results. If you charge per unit, you must adjust your pricing model for Dysport or accept lower per-unit margins to remain competitive.

What is the difference between Botox Xeomin and Jeuveau dosing?

Botox, Xeomin, and Jeuveau have similar unit potency and require comparable doses (~20 units for glabellar treatment), making them interchangeable for pricing and scheduling purposes. Dysport is the outlier, requiring roughly 2.5–3× more units for the same effect.

Does Daxxify need to be refrigerated like Botox?

No—Daxxify is lyophilized (powder form) and room-temperature stable, while Botox, Dysport, Xeomin, and Jeuveau require refrigeration. Daxxify's stability reduces waste, storage costs, and inventory management complexity, improving your cash flow and margins.

How much should I charge per unit for neurotoxins?

Pricing depends on your wholesale cost per unit (which varies by volume, distributor, and contract terms), local competition, and patient demand. Calculate your net cost after volume discounts from suppliers like Henry Schein or Medline, then apply your desired margin—typically 100–200% markup is standard in med-spas, but adjust based on your market position.

Neurotoxin Comparison: Botox vs Dysport vs Jeuveau vs Daxxify vs Xeomin

Side-by-side breakdown of onset, duration, dosing, and cost to help you stock the right products and set competitive pricing.

Neurotoxins are the backbone of most med-spa revenue. But each product differs in speed of action, longevity, unit potency, and wholesale cost—factors that directly affect your patient experience, repeat-visit cadence, and margins. This guide compares the five FDA-approved neurotoxins currently available in the U.S. aesthetic market, so you can make informed stocking and pricing decisions.

Onset and Duration: Why Timing Matters

Onset (how fast results appear) and duration (how long results last) are the two variables patients ask about first—and they drive your scheduling and revenue predictability.

Botox (onabotulinumtoxinA, Allergan): typically 3–7 days visible effect, full results by day 14; lasts ~3–4 months
Dysport (abobotulinumtoxinA, Galderma): often 2–3 days visible, full effect by day 7; lasts ~3–4 months
Jeuveau (prabotulinumtoxinA, Evolus): 2–3 days visible, full effect by day 7; lasts ~3–4 months
Xeomin (incobotulinumtoxinA, Merz): 3–7 days visible, full effect by day 14; lasts ~3–4 months
Daxxify (daxibotulinumtoxinA, Revance): 2–3 days visible, full effect by day 7; lasts up to 6 months (unique advantage)

Interpretation: Dysport, Jeuveau, and Daxxify appeal to patients wanting faster results. Daxxify's extended duration reduces visit frequency—attractive for busy patients but potentially lower annual visit count. Botox and Xeomin's slower onset may suit patients who prefer gradual change.

Unit Potency and Dosing: The Math Behind Pricing

Not all units are equal. Unit potency varies by product, meaning the same anatomical area may require different unit counts.

Botox: 1 unit = 1 unit (reference standard); typical glabellar dose ~20 units
Dysport: ~2.5–3× less potent per unit than Botox; typical glabellar dose ~50 units (roughly equivalent effect)
Jeuveau: similar potency to Botox; typical glabellar dose ~20 units
Xeomin: similar potency to Botox; typical glabellar dose ~20 units
Daxxify: similar potency to Botox; typical glabellar dose ~20 units

Interpretation: If you charge per unit, Dysport patients receive more units for similar results—you must adjust pricing accordingly or accept lower per-unit margins. Jeuveau, Xeomin, and Daxxify align with Botox dosing, simplifying cross-product comparisons. Always verify your specific wholesale cost per unit to ensure profitability.

Wholesale Cost and Margin Structure

Neurotoxin wholesale pricing varies by volume, contract terms, and distributor. Do not rely on list prices; negotiate with your supplier. Key factors:

Volume discounts: larger orders typically yield 10–20% better per-unit cost
Loyalty/exclusivity agreements: some manufacturers offer rebates or tiered pricing for higher market share
Distributor markup: varies (typically 20–40% above manufacturer cost)
Shelf life: Botox, Dysport, Xeomin, and Jeuveau require refrigeration; Daxxify is lyophilized (powder) and room-temperature stable, reducing waste and storage costs

Interpretation: Request current pricing from your distributor (e.g., Henry Schein, Medline, Galderma Direct) and calculate your cost per unit for each product. Room-temperature stability of Daxxify may reduce waste and improve cash flow. Compare net cost after volume discounts before committing to a product mix.

Market Position and Patient Preference

Each neurotoxin has carved a niche:

Botox: market leader; highest brand recognition; most clinical data; preferred by conservative patients
Dysport: faster onset appeals to patients wanting quick results; strong in competitive markets
Jeuveau: newer entrant; marketed as "millennial Botox"; lower list price (historically); appeals to price-sensitive patients
Xeomin: no additives ("naked" toxin); appeals to patients concerned about antibody formation; smaller market share
Daxxify: longest duration; premium positioning; appeals to patients wanting fewer visits; growing adoption

Interpretation: Stock at least two products to offer choice and hedge supply risk. Botox remains the safest default. Daxxify's extended duration justifies premium pricing and may increase patient lifetime value. Jeuveau and Dysport compete on speed and price—useful for volume-driven practices. Xeomin serves a niche but smaller patient base.

Pricing Strategy: Per-Unit vs. Per-Area

Two common models:

Per-unit pricing: charge $X per unit (e.g., $12–$15/unit for Botox, $8–$12/unit for Dysport). Transparent, scalable, but requires patient education on unit counts.

Per-area pricing: charge a flat fee per anatomical region (e.g., $200–$300 for glabellar lines, $150–$250 for forehead). Simpler for patients, but requires you to absorb unit variance and product cost differences.

Interpretation: Per-unit pricing aligns cost with product potency and your wholesale cost. If using Dysport (more units needed), per-unit pricing protects your margin. Per-area pricing works if you standardize dosing and product mix. Most profitable practices use per-unit pricing and adjust the per-unit rate by product to maintain consistent margins (e.g., Botox $14/unit, Dysport $9/unit, Daxxify $16/unit).

Regulatory and Supply Considerations

All five neurotoxins are FDA-approved for glabellar lines (frown lines). Expanded indications vary:

Botox: forehead, crow's feet, neck bands, hyperhidrosis, migraine
Dysport: forehead, crow's feet
Jeuveau: glabellar lines only (as of latest FDA approval)
Xeomin: glabellar lines, forehead
Daxxify: glabellar lines, forehead, crow's feet

Supply: All are manufactured by large pharmaceutical companies (Allergan/AbbVie, Galderma, Evolus, Merz, Revance). Check the FDA's official product database and your state's pharmacy/medical board for current approvals and any supply alerts. Verify your distributor's inventory and lead times before committing to a product mix.

Bottom line

Choose your neurotoxin mix based on onset speed, duration, unit potency, wholesale cost, and patient demand—then price per unit to maintain consistent margins across products.