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SAFETYTirzepatide (Mounjaro/Zepbound) — 140,435 adverse-event reportsFDA CLEAREDIntense Pulsed Light Therapy Device — Sanhe LEFIS Electronics Co., Ltd.Bausch Health (Solta) -8.71%SAFETYSemaglutide (Wegovy/Ozempic) — 82,911 adverse-event reportsFDA CLEAREDBarbed PDO Suture — Sutura Medical Technology, Inc.STRATA Skin Sciences +8.33%SAFETYBotox — 75,499 adverse-event reportsFDA CLEAREDERBECRYO 2 Cryosurgical Unit and Accessories — Erbe Elektromedizin GmbHThe Beauty Health Company (HydraFacial) -7.17%FDA CLEAREDLumiGlam Laser System (SHE-LSP601-3) — Beijing Sano Laser S&T Development Co.,LtdEli Lilly +7.04%FDA CLEAREDCurrentBody Skin LED Multi Light Therapy Mask (MK-110D) — The Beauty Tech Group, Ltd.STAAR Surgical -5.13%RECALLFDA recall: PAYLESS COMPOUNDERS, LLC — Semaglutide-Glycine-Cyanocobalamin Injectable, 2.5 RECALLFDA recall: HTO Nevada Inc. dba Kirkman — MAXIMUM, ZONE 1, 4% Lidocaine Cream, 1/2 oz bottRECALLFDA recall: Pro Numb Tattoo Numbing Spray LLC — Pro Numb Tattoo Numbing Spray, For Sensiti
Sun Protection

Zinc Oxide

Broad-spectrum mineral UV blocker; physical sunscreen workhorse.

Also known as: Zinc oxide, ZnO, calamine (when mixed with iron oxides); same name in INCI.

What it is
Zinc oxide is an inorganic mineral powder that sits on the skin surface and reflects and scatters both UVA and UVB rays. It is non-nano or nano-sized depending on formulation, with nano particles offering better cosmetic elegance but raising some safety questions.
What it does
Zinc oxide provides immediate, broad-spectrum UV protection (UVA and UVB) without requiring absorption into the skin. It also has mild anti-inflammatory and soothing properties, making it calming for sensitive or compromised skin. Unlike chemical sunscreens, it does not degrade in sunlight and remains effective throughout the day.
The evidence
Strong clinical evidence supports zinc oxide as an effective broad-spectrum UV blocker; it is FDA-approved as a Category I sunscreen active. Multiple studies confirm its stability and non-irritating profile, though nano-particle safety data remains moderate and ongoing.
Best for
Sensitive, reactive, rosacea-prone, and post-procedure skin; ideal for those with chemical sunscreen sensitivities or allergies.
Pairs well with
Titanium dioxide (complementary mineral blocker), silicones (improve spreadability), iron oxides (add tint and reduce white cast), hydrating humectants like glycerin.
Use cautiously with
No major conflicts; generally compatible with most skincare actives. Avoid layering excessively thick formulations that may feel occlusive on very oily skin.
Cautions
Non-nano zinc oxide is safe in pregnancy and nursing. Nano-particle formulations have not been conclusively proven unsafe but are not recommended during pregnancy without dermatologist approval. May leave a white cast on deeper skin tones unless tinted or micronized.
General information, not medical advice. Ingredient effects vary by formulation, concentration, and skin. Patch-test new actives and consult a qualified provider before starting prescription ingredients.

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