Compliance · Live FDA data
Aesthetic Safety Signals
Adverse-event report counts for the injectables, fillers, and devices you use — pulled from the FDA's FAERS (drugs) and MAUDE (devices) databases. 340,356 reports tracked across 15 products.
Read these carefully — they are signals, not verdicts. An adverse-event report does not prove the product caused the event. Counts are not adjusted for how widely a product is used, anyone can file a report, and totals reflect all reported history. Use this to know what to watch and ask about — not to rank products.
Neurotoxin
Botox
FAERS75,499reports
19%serious
Most-reported reactions
Drug Ineffective 26,371
Off Label Use 11,277
Therapeutic Response Decreased 4,504
Headache 4,025
Product Preparation Error 3,655
Dysport
FAERS6,783reports
29%serious
Most-reported reactions
Off Label Use 2,429
Drug Ineffective 1,806
Product Preparation Error 756
Headache 464
Muscular Weakness 371
Xeomin
FAERS5,427reports
14%serious
Most-reported reactions
Drug Ineffective 1,785
Off Label Use 1,194
Therapeutic Response Decreased 695
Injection Site Pain 329
Product Preparation Issue 196
Jeuveau
FAERS3,770reports
2%serious
Most-reported reactions
Drug Ineffective 1,587
Off Label Use 1,312
Therapeutic Product Effect Decreased 715
Drug Effect Less Than Expected 469
Headache 170
Daxxify
FAERS46reports
41%serious
Most-reported reactions
Drug Ineffective 11
Eyelid Ptosis 6
Headache 6
Influenza Like Illness 4
Anxiety 3
Dermal filler
Juvederm
MAUDE9,535reports
87%serious
Sculptra
MAUDE1,984reports
52%serious
Radiesse
MAUDE1,614reports
75%serious
Restylane
MAUDE1,201reports
79%serious
Energy device
CoolSculpting
MAUDE11,042reports
98%serious
Morpheus8
MAUDE61reports
100%serious
Ultherapy
MAUDE42reports
93%serious
Emsculpt
MAUDE6reports
83%serious
GLP-1 (weight-loss demand driver)
Tirzepatide (Mounjaro/Zepbound)
FAERS140,435reports
17%serious
Most-reported reactions
Incorrect Dose Administered 28,115
Nausea 14,290
Injection Site Pain 13,177
Extra Dose Administered 9,000
Diarrhoea 8,305
Semaglutide (Wegovy/Ozempic)
FAERS82,911reports
54%serious
Most-reported reactions
Nausea 12,084
Vomiting 7,988
Off Label Use 7,322
Diarrhoea 6,943
Decreased Appetite 4,963
When a safety signal turns into a recall, know first.
We watch these databases continuously. Inside MedSpa Pro flags the moment a product you use spikes, gets a warning, or hits a recall — and what to do about it.
Go Pro · $20/moSource: openFDA FAERS & MAUDE. General information only — not medical, safety, or regulatory advice. Inside MedSpa is a general, impersonal publication for medical-aesthetics business owners. It is not individualized business, financial, medical, or legal advice. Any market or company information is general in nature and not a recommendation.