Who can inject
MD, DO, NP, PA, RN under physician supervision
Registered nurses (RNs)
Yes, under physician supervision and delegation; must work in facility with supervising physician present or on-call
Nurse practitioners & physician assistants
NP/PA may inject under physician supervision; independent practice not permitted for injectables
The exam that makes it legal
Required; in-person exam mandatory before treatment A valid order or good-faith exam by an authorized provider is what makes an injection lawful — not simply who holds the syringe.
Training expected
No state-mandated injector training beyond licensure; however, physician supervision and facility protocols typically require documented training.
What to verify in California
Ensure a California-licensed physician is the controlling owner or medical director with clear supervisory authority over all injectors.
Primary source: Medical Board of California; California Board of Registered Nursing
General business information for California medical-spa owners, current as of 2026 — not legal advice. State boards update rules often; confirm specifics with the California board (and your own counsel) before you act.