Who can inject
MD, DO, NP, PA, RN under physician supervision/delegation
Registered nurses (RNs)
Yes, under physician delegation and direct supervision; must work in facility with supervising physician present or on-site
Nurse practitioners & physician assistants
NP/PA may inject under physician supervision; independent practice not permitted for injectables
The exam that makes it legal
Required; in-person exam mandatory before treatment A valid order or good-faith exam by an authorized provider is what makes an injection lawful — not simply who holds the syringe.
Training expected
No state-mandated injector training beyond licensure; however, facility protocols and physician delegation agreements typically require documented training.
What to verify in California
Verify physician ownership or establish compliant MSO with physician control; confirm on-site supervising physician availability for all injection days.
Primary source: California Medical Board; California Board of Registered Nursing
General business information for California medical-spa owners, current as of 2026 — not legal advice. State boards update rules often; confirm specifics with the California board (and your own counsel) before you act.