Registered nurses (RNs)

Yes, under physician supervision and delegation; must work in facility with supervising physician present or on-call

Nurse practitioners & physician assistants

NP/PA may inject under physician supervision; independent practice not permitted for injectables

Supervision & the medical director

Required; supervising physician must be on-site or on-call and responsible for all injections

The exam requirement

Required; in-person exam mandatory before treatment

What to verify in California

Ensure a California-licensed physician is the controlling owner or medical director with clear supervisory authority over all injectors.

Primary source: Medical Board of California; California Board of Registered Nursing

General business information for California medical-spa owners, current as of 2026 — not legal advice. State boards update rules often; confirm specifics with the California board (and your own counsel) before you act.

See the full California regulation profile →