Registered nurses (RNs)

Yes, under physician delegation and direct supervision; must work in facility with supervising physician present or on-site

Nurse practitioners & physician assistants

NP/PA may inject under physician supervision; independent practice not permitted for injectables

Supervision & the medical director

Required; physician must be on-site or immediately available for injectable procedures

The exam requirement

Required; in-person exam mandatory before treatment

What to verify in California

Verify physician ownership or establish compliant MSO with physician control; confirm on-site supervising physician availability for all injection days.

Primary source: California Medical Board; California Board of Registered Nursing

General business information for California medical-spa owners, current as of 2026 — not legal advice. State boards update rules often; confirm specifics with the California board (and your own counsel) before you act.

See the full California regulation profile →