Who can inject
MD/DO only; RN/NP/PA may not inject neurotoxins or fillers
Registered nurses (RNs)
No; RNs cannot inject neurotoxins or fillers in Illinois
Nurse practitioners & physician assistants
NP/PA cannot inject neurotoxins/fillers; physician collaboration does not permit independent injection
The exam that makes it legal
Good-faith exam required; in-person only A valid order or good-faith exam by an authorized provider is what makes an injection lawful — not simply who holds the syringe.
Training expected
No state-mandated injector training beyond licensure.
What to verify in Illinois
Ensure a licensed MD/DO owns or controls the medical spa and performs all injections; verify CPOM compliance with Illinois Department of Financial and Professional Regulation.
Primary source: Illinois Department of Financial and Professional Regulation (IDFPR), Medical Board
General business information for Illinois medical-spa owners, current as of 2026 — not legal advice. State boards update rules often; confirm specifics with the Illinois board (and your own counsel) before you act.