Who can inject
MD/DO only; RN/LPN/NP/PA cannot inject neurotoxins or fillers
Registered nurses (RNs)
No; Illinois prohibits RN injection of neurotoxins and fillers
Nurse practitioners & physician assistants
Limited; NP/PA cannot independently inject neurotoxins/fillers; physician collaboration required but does not permit delegation for injections
The exam that makes it legal
Required; in-person exam mandatory before any treatment A valid order or good-faith exam by an authorized provider is what makes an injection lawful — not simply who holds the syringe.
Training expected
No state-mandated injector training beyond MD/DO licensure.
What to verify in Illinois
If you are not a physician, establish a physician-owned or physician-controlled MSO structure; verify that your medical director meets on-site or availability requirements under Illinois State Medical Practice Act.
Primary source: Illinois State Medical Board; Illinois Department of Financial and Professional Regulation (IDFPR)
General business information for Illinois medical-spa owners, current as of 2026 — not legal advice. State boards update rules often; confirm specifics with the Illinois board (and your own counsel) before you act.