Who can inject

MD/DO, NP/PA under physician supervision, RN under physician delegation

Registered nurses (RNs)

Yes, under physician delegation and direct supervision

Nurse practitioners & physician assistants

NP/PA may inject under physician supervision and collaboration

The exam that makes it legal

Good-faith exam required; in-person or telehealth allowed under physician discretion A valid order or good-faith exam by an authorized provider is what makes an injection lawful — not simply who holds the syringe.

Training expected

No state-mandated injector training beyond licensure.

What to verify in Indiana

Establish a written physician supervision agreement and ensure all RN/NP/PA injectors are properly delegated and documented with the supervising physician.

Primary source: Indiana Medical Licensing Board, Indiana State Board of Nursing

General business information for Indiana medical-spa owners, current as of 2026 — not legal advice. State boards update rules often; confirm specifics with the Indiana board (and your own counsel) before you act.

See the full Indiana regulation profile →