Who can inject

MD/DO, NP/PA under physician supervision, RN under physician delegation

Registered nurses (RNs)

Yes, under physician delegation and supervision

Nurse practitioners & physician assistants

Require physician collaboration/supervision for injections

The exam that makes it legal

Required; in-person preferred, telehealth conditional A valid order or good-faith exam by an authorized provider is what makes an injection lawful — not simply who holds the syringe.

Training expected

No state-mandated injector training beyond licensure.

What to verify in Minnesota

Establish written delegation and supervision agreements with your medical director and verify compliance with Minnesota Board of Medical Practice guidance on RN/NP scope.

Primary source: Minnesota Board of Medical Practice; Minnesota Board of Nursing

General business information for Minnesota medical-spa owners, current as of 2026 — not legal advice. State boards update rules often; confirm specifics with the Minnesota board (and your own counsel) before you act.

See the full Minnesota regulation profile →