Who can inject

MD/DO, NP/PA under physician supervision, RN under physician delegation

Registered nurses (RNs)

Yes, under physician delegation and supervision

Nurse practitioners & physician assistants

May inject under physician supervision; independent practice not permitted for injections

The exam that makes it legal

Required; in-person exam generally required before treatment A valid order or good-faith exam by an authorized provider is what makes an injection lawful — not simply who holds the syringe.

Training expected

No state-mandated injector training beyond licensure; facility-specific training and competency verification recommended

What to verify in Minnesota

Establish a written delegation and supervision agreement with your medical director and confirm compliance with Minnesota Board of Medical Practice on RN/NP/PA scope and good-faith exam requirements.

Primary source: Minnesota Board of Medical Practice

General business information for Minnesota medical-spa owners, current as of 2026 — not legal advice. State boards update rules often; confirm specifics with the Minnesota board (and your own counsel) before you act.

See the full Minnesota regulation profile →