Can registered nurses and nurse practitioners inject Botox and fillers in Minnesota?

Yes, under physician delegation and supervision Require physician collaboration/supervision for injections

Minnesota · Moderate

Can RNs and Nurse Practitioners Inject Botox in Minnesota?

Nurses do most of the injecting in this industry — but Minnesota draws specific lines around what an RN versus an NP can do, and who has to supervise.

By Evan at Inside MedSpa

Registered nurses (RNs)

Yes, under physician delegation and supervision

Nurse practitioners & physician assistants

Require physician collaboration/supervision for injections

Supervision & the medical director

Required for medical spa operations

The exam requirement

Required; in-person preferred, telehealth conditional

What to verify in Minnesota

Establish written delegation and supervision agreements with your medical director and verify compliance with Minnesota Board of Medical Practice guidance on RN/NP scope.

Primary source: Minnesota Board of Medical Practice; Minnesota Board of Nursing

General business information for Minnesota medical-spa owners, current as of 2026 — not legal advice. State boards update rules often; confirm specifics with the Minnesota board (and your own counsel) before you act.

See the full Minnesota regulation profile →

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