Who can inject
MD, DO, NP, PA, RN under physician supervision
Registered nurses (RNs)
Yes, under physician delegation and supervision
Nurse practitioners & physician assistants
NP/PA may inject under physician collaboration; independent practice limited
The exam that makes it legal
Required; in-person exam before treatment A valid order or good-faith exam by an authorized provider is what makes an injection lawful — not simply who holds the syringe.
Training expected
No state-mandated injector training beyond licensure.
What to verify in Maine
Establish a written physician-supervision agreement and ensure the medical director is licensed in Maine and actively involved in protocol development and oversight.
Primary source: Maine Medical Board; Maine Board of Nursing
General business information for Maine medical-spa owners, current as of 2026 — not legal advice. State boards update rules often; confirm specifics with the Maine board (and your own counsel) before you act.