Who can inject

MD, DO, NP, PA, RN under physician supervision

Registered nurses (RNs)

Yes, under physician delegation and supervision

Nurse practitioners & physician assistants

NP/PA may inject under physician collaboration; independent practice limited

The exam that makes it legal

Required; in-person exam before treatment A valid order or good-faith exam by an authorized provider is what makes an injection lawful — not simply who holds the syringe.

Training expected

No state-mandated injector training beyond licensure.

What to verify in Maine

Establish a written physician-supervision agreement and ensure the medical director is licensed in Maine and actively involved in protocol development and oversight.

Primary source: Maine Medical Board; Maine Board of Nursing

General business information for Maine medical-spa owners, current as of 2026 — not legal advice. State boards update rules often; confirm specifics with the Maine board (and your own counsel) before you act.

See the full Maine regulation profile →