Registered nurses (RNs)

Yes, under physician delegation and supervision

Nurse practitioners & physician assistants

May inject under physician collaboration; independent practice varies by scope

Supervision & the medical director

Not statutorily required, but recommended for oversight

The exam requirement

Required; in-person or telehealth allowed if physician-patient relationship established

What to verify in Maine

Establish clear delegation and supervision protocols with your collaborating physician and document the physician-patient relationship for any telehealth good-faith exams.

Primary source: Maine Board of Licensure in Medicine

General business information for Maine medical-spa owners, current as of 2026 — not legal advice. State boards update rules often; confirm specifics with the Maine board (and your own counsel) before you act.

See the full Maine regulation profile →