Registered nurses (RNs)
Yes, under physician delegation and supervision
Nurse practitioners & physician assistants
May inject under physician collaboration; independent practice varies by scope
Supervision & the medical director
Not statutorily required, but recommended for oversight
The exam requirement
Required; in-person or telehealth allowed if physician-patient relationship established
What to verify in Maine
Establish clear delegation and supervision protocols with your collaborating physician and document the physician-patient relationship for any telehealth good-faith exams.
Primary source: Maine Board of Licensure in Medicine
General business information for Maine medical-spa owners, current as of 2026 — not legal advice. State boards update rules often; confirm specifics with the Maine board (and your own counsel) before you act.