Can registered nurses and nurse practitioners inject Botox and fillers in Maine?

Yes, under physician delegation and supervision NP/PA may inject under physician collaboration; independent practice limited

Maine · Moderate

Can RNs and Nurse Practitioners Inject Botox in Maine?

Nurses do most of the injecting in this industry — but Maine draws specific lines around what an RN versus an NP can do, and who has to supervise.

By Evan at Inside MedSpa

Registered nurses (RNs)

Yes, under physician delegation and supervision

Nurse practitioners & physician assistants

NP/PA may inject under physician collaboration; independent practice limited

Supervision & the medical director

Required for medical spa; physician oversight mandatory

The exam requirement

Required; in-person exam before treatment

What to verify in Maine

Establish a written physician-supervision agreement and ensure the medical director is licensed in Maine and actively involved in protocol development and oversight.

Primary source: Maine Medical Board; Maine Board of Nursing

General business information for Maine medical-spa owners, current as of 2026 — not legal advice. State boards update rules often; confirm specifics with the Maine board (and your own counsel) before you act.

See the full Maine regulation profile →

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