Who can inject

MD/DO, NP/PA under physician supervision, RN under physician delegation

Registered nurses (RNs)

Yes, under physician delegation and supervision; scope varies by board interpretation

Nurse practitioners & physician assistants

Require physician collaboration/supervision for injections

The exam that makes it legal

Required; in-person preferred, telehealth conditional A valid order or good-faith exam by an authorized provider is what makes an injection lawful — not simply who holds the syringe.

Training expected

No state-mandated injector training beyond licensure.

What to verify in Michigan

Verify with the Michigan Department of Licensing and Regulatory Affairs (LARA) that your medical director's supervision protocols comply with current board guidance on RN/NP delegation.

Primary source: Michigan Department of Licensing and Regulatory Affairs (LARA); Board of Medicine; Board of Nursing

General business information for Michigan medical-spa owners, current as of 2026 — not legal advice. State boards update rules often; confirm specifics with the Michigan board (and your own counsel) before you act.

See the full Michigan regulation profile →