Registered nurses (RNs)

Yes, under physician delegation and direct supervision

Nurse practitioners & physician assistants

May inject under physician supervision; independent practice not permitted for injections

Supervision & the medical director

Required; physician must supervise and oversee injection protocols

The exam requirement

Required; in-person exam generally required, telehealth varies by board interpretation

What to verify in Michigan

Establish a clear written delegation and supervision agreement with your medical director and verify compliance with Michigan LARA's current guidance on RN and NP/PA scope.

Primary source: Michigan Department of Licensing and Regulatory Affairs (LARA) / Michigan Medical Board

General business information for Michigan medical-spa owners, current as of 2026 — not legal advice. State boards update rules often; confirm specifics with the Michigan board (and your own counsel) before you act.

See the full Michigan regulation profile →