Can registered nurses and nurse practitioners inject Botox and fillers in South Carolina?

Yes, under physician delegation and supervision NP/PA may inject under physician collaboration; independent practice varies by setting

South Carolina · Moderate

Can RNs and Nurse Practitioners Inject Botox in South Carolina?

Nurses do most of the injecting in this industry — but South Carolina draws specific lines around what an RN versus an NP can do, and who has to supervise.

By Evan at Inside MedSpa

Registered nurses (RNs)

Yes, under physician delegation and supervision

Nurse practitioners & physician assistants

NP/PA may inject under physician collaboration; independent practice varies by setting

Supervision & the medical director

Required for non-physician-owned facilities

The exam requirement

Required; in-person or telehealth allowed

What to verify in South Carolina

Verify medical director credentials and ensure written delegation/supervision protocols for all injectors are documented.

Primary source: South Carolina Medical Board; Board of Nursing

General business information for South Carolina medical-spa owners, current as of 2026 — not legal advice. State boards update rules often; confirm specifics with the South Carolina board (and your own counsel) before you act.

See the full South Carolina regulation profile →

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