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Antioxidants

Green Tea (EGCG)

Potent antioxidant polyphenol that neutralizes free radicals and inflammation.

Also known as: EGCG (epigallocatechin gallate), Camellia sinensis extract, green tea polyphenols, catechins.

What it is
EGCG is the most abundant and bioactive catechin polyphenol found in green tea leaves. It's a plant-derived antioxidant that crosses the skin barrier and accumulates in dermal tissue.
What it does
EGCG scavenges free radicals and reduces oxidative stress, which slows collagen breakdown and supports skin barrier function. It also has mild anti-inflammatory and antimicrobial properties, making it useful for calming irritation and supporting acne-prone skin. Studies show it can reduce sebum production and improve skin texture over time.
The evidence
Strong clinical evidence supports EGCG's antioxidant and anti-inflammatory effects in topical skincare; multiple randomized controlled trials confirm benefits for photoaging, acne, and sebum control. Evidence for significant collagen synthesis is moderate.
Best for
All skin types, especially oily, acne-prone, and sun-damaged skin; also beneficial for sensitive and aging skin seeking antioxidant protection.
Pairs well with
Vitamin C, niacinamide, hyaluronic acid, resveratrol, and other antioxidants; works synergistically with SPF for photoprotection.
Use cautiously with
No major conflicts. Can be used alongside most actives; avoid excessive heat during formulation as EGCG degrades above 60°C.
Cautions
Generally well-tolerated; rare sensitization in very sensitive skin. Formulations must be stabilized (pH 3–5, antioxidant co-factors) to prevent oxidation and loss of potency.
General information, not medical advice. Ingredient effects vary by formulation, concentration, and skin. Patch-test new actives and consult a qualified provider before starting prescription ingredients.

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