Can registered nurses and nurse practitioners inject Botox and fillers in Indiana?

Yes, under physician delegation and direct supervision Can inject under physician supervision; independent practice not permitted for injections

Indiana · Moderate

Can RNs and Nurse Practitioners Inject Botox in Indiana?

Nurses do most of the injecting in this industry — but Indiana draws specific lines around what an RN versus an NP can do, and who has to supervise.

By Evan at Inside MedSpa

Registered nurses (RNs)

Yes, under physician delegation and direct supervision

Nurse practitioners & physician assistants

Can inject under physician supervision; independent practice not permitted for injections

Supervision & the medical director

Required for RN/LPN injectors; physician supervision and delegation mandatory

The exam requirement

Required; in-person or telehealth allowed if physician-patient relationship established

What to verify in Indiana

Establish a written delegation and supervision agreement with your medical director; ensure compliance with Indiana's telemedicine rules if offering remote consultations.

Primary source: Indiana Medical Licensing Board; Indiana State Board of Nursing

General business information for Indiana medical-spa owners, current as of 2026 — not legal advice. State boards update rules often; confirm specifics with the Indiana board (and your own counsel) before you act.

See the full Indiana regulation profile →

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