Can registered nurses and nurse practitioners inject Botox and fillers in Indiana?

Yes, under physician delegation and direct supervision NP/PA may inject under physician supervision and collaboration

Indiana · Moderate

Can RNs and Nurse Practitioners Inject Botox in Indiana?

Nurses do most of the injecting in this industry — but Indiana draws specific lines around what an RN versus an NP can do, and who has to supervise.

By Evan at Inside MedSpa

Registered nurses (RNs)

Yes, under physician delegation and direct supervision

Nurse practitioners & physician assistants

NP/PA may inject under physician supervision and collaboration

Supervision & the medical director

Medical director/supervising physician required for medical spa operations

The exam requirement

Good-faith exam required; in-person or telehealth allowed under physician discretion

What to verify in Indiana

Establish a written physician supervision agreement and ensure all RN/NP/PA injectors are properly delegated and documented with the supervising physician.

Primary source: Indiana Medical Licensing Board, Indiana State Board of Nursing

General business information for Indiana medical-spa owners, current as of 2026 — not legal advice. State boards update rules often; confirm specifics with the Indiana board (and your own counsel) before you act.

See the full Indiana regulation profile →

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